Description

Di-T-Butyl(3-Sulfonatopropyl)Phosphine is a high-purity, water-soluble phosphine ligand, essential for advanced catalytic processes. Its primary value lies in enabling efficient and selective cross-coupling reactions under aqueous or biphasic conditions, which are critical for sustainable chemical manufacturing. This compound is particularly sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new synthetic routes and scaling up production.

Application

• Aqueous-Phase Catalysis: As a key ligand for palladium and other transition metal catalysts in Suzuki, Heck, and Sonogashira cross-coupling reactions performed in water.
• Pharmaceutical Intermediate Synthesis: For the production of complex drug molecules and active pharmaceutical ingredients (APIs) where water-soluble catalysts are advantageous.
• Agrochemical Manufacturing: In the synthesis of novel herbicides, fungicides, and insecticides requiring selective C-C and C-N bond formation.
• Material Science Research: For the development of functional polymers and nanomaterials via controlled polymerization or surface modification techniques.
• Homogeneous Catalysis: Facilitating challenging organic transformations that benefit from the electron-donating and stabilizing properties of the tert-butylphosphine group.
• Ligand for Metal Recovery: Its sulfonate group aids in catalyst recovery and recycling in biphasic systems, improving process economics.

Basic Information

Product Name	Di-T-Butyl(3-Sulfonatopropyl)Phosphine
CAS No.	1055888-89-5
Molecular Formula	C11H25O3PS
Molecular Weight	268.35 g/mol
Synonyms	Di-tert-Butyl(3-sulfonatopropyl)phosphine; 3-(Di-tert-butylphosphino)propane-1-sulfonate; Di-t-Butylphosphinopropanesulfonic Acid; DTBPPS; Sulfonated Di-tert-butylphosphine; Water-Soluble Di-tert-butylphosphine Ligand; (3-Sulfonatopropyl)di-tert-butylphosphine
EINECS	Contact for details

Quality Control

Every batch of Di-T-Butyl(3-Sulfonatopropyl)Phosphine is manufactured and tested to meet stringent purity standards, with a minimum assay of 98%. Our quality assurance protocol includes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from NMR, HPLC, and titration methods are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be kept sealed to exclude moisture and air. Avoid prolonged exposure to ambient conditions.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	Min. 98.0%
Water Content (KF)	Max. 1.0%
Residue on Ignition	Max. 0.1%
Heavy Metals (as Pb)	Max. 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.