Description

2-[(11Bs)-3,5-Dihydro-4H-Dinaphtho[2,1-C:1',2'-E]Phosphepin-4-Yl]Ethyl]Amine, Min. 97% is a high-purity, chiral phosphine-based ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly selective and efficient chemical transformations, which are essential for producing enantiomerically pure intermediates in pharmaceutical and fine chemical synthesis. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel synthetic routes and optimizing manufacturing processes.

Application

• Asymmetric Hydrogenation: As a chiral ligand for transition metal catalysts (e.g., Rh, Ru, Ir) in the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: For the production of single-enantiomer active pharmaceutical ingredients (APIs) where high stereochemical purity is mandated.
• Cross-Coupling Reactions: Facilitating asymmetric C-C and C-X bond-forming reactions, such as Suzuki-Miyaura or Buchwald-Hartwig amination, with improved selectivity.
• Agrochemical Research: Development of chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profiles.
• Academic & Industrial R&D: Serving as a key reagent in methodological studies for discovering new catalytic systems and reaction mechanisms.
• Fine Chemical Production: Synthesis of specialty chemicals, flavors, and fragrances requiring precise stereochemical control.

Basic Information

Product Name	2-[(11Bs)-3,5-Dihydro-4H-Dinaphtho[2,1-C:1',2'-E]Phosphepin-4-Yl]Ethyl]Amine, Min. 97%
CAS No.	1053659-64-5
Molecular Formula	C26H22NP
Molecular Weight	379.44 g/mol
Synonyms	(S)-2-((3,5-Dihydro-4H-dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl)ethyl)amine; (S)-2-(Dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl)ethanamine; (S)-2-(4H-Dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl)ethylamine; (S)-2-(3,5-Dihydro-4H-dinaphtho[2,1-c:1',2'-e]phosphepin-4-yl)ethan-1-amine; (S)-2-(Dinaphthophosphepin-4-yl)ethylamine; (S)-DNPEN; Chiral DNPEN ligand; (S)-4-(2-Aminoethyl)-4H-dinaphtho[2,1-c:1',2'-e]phosphepine
EINECS	Contact for details

Quality Control

Our 2-[(11Bs)-3,5-Dihydro-4H-Dinaphtho[2,1-C:1',2'-E]Phosphepin-4-Yl]Ethyl]Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the specified minimum 97% purity and consistent performance as a ligand. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0% ee
Loss on Drying	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.