Description

n-(2-Methoxyphenyl)-2-(Di-T-Butylphosphino)Pyrrole, 92% [Catacxium Pometb] is a specialized, high-purity organophosphorus ligand used in advanced catalytic transformations. This compound matters for its critical role in facilitating challenging cross-coupling reactions, enabling the efficient synthesis of complex molecules with high selectivity and yield. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and optimizing synthetic routes. The product is supplied at a purity of 92%, balancing performance with commercial viability for industrial-scale applications.

Application

• As a highly effective ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig amination, and Negishi couplings.
• For the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs) requiring selective C-C and C-N bond formation.
• In the development and production of agrochemicals, including advanced herbicides, fungicides, and insecticides.
• As a key component in catalyst systems for fine chemical and specialty material manufacturing.
• For academic and industrial research into new catalytic methodologies and reaction optimization.
• In process chemistry for the scale-up of coupling reactions from laboratory to pilot plant and production scales.

Basic Information

Product Name	n-(2-Methoxyphenyl)-2-(Di-T-Butylphosphino)Pyrrole,92% [Catacxium Pometb]
CAS No.	1053658-91-5
Molecular Formula	C19H26NOP
Molecular Weight	315.39 g/mol
Synonyms	Catacxium Pometb; 2-(Di-tert-butylphosphino)-N-(2-methoxyphenyl)-1H-pyrrole; 2-(Di-tert-butylphosphino)-N-(2-methoxyphenyl)pyrrole; n-(2-Methoxyphenyl)-2-(di-tert-butylphosphino)-1H-pyrrole; 2-(Di-T-Butylphosphino)-N-(2-Methoxyphenyl)Pyrrole; Pometb; Phosphine Ligand Pometb; Buchwald Ligand
EINECS	Contact for details

Quality Control

Our n-(2-Methoxyphenyl)-2-(Di-T-Butylphosphino)Pyrrole, 92% is manufactured under strict quality protocols to ensure batch-to-batch consistency and performance reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key specifications to support your quality assurance and regulatory needs. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and maintain stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 92.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.