Description

2-(Di-T-Butylphosphino)Ethylamine, Min. 97% (10 Wt% In Thf) is a specialized organophosphorus ligand precursor, supplied as a stabilized solution in tetrahydrofuran (THF) for enhanced handling and shelf-life. This compound is critical for the synthesis of advanced catalysts used in cross-coupling reactions, enabling efficient and selective bond formation in complex organic syntheses. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and high-value intermediates.

Application

• As a key precursor for Buchwald-type biarylphosphine ligands in palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination).
• In the development of homogeneous catalysts for C-N, C-O, and C-C bond formation in pharmaceutical API synthesis.
• For the preparation of specialized ligands used in asymmetric hydrogenation and other enantioselective transformations.
• As a research chemical in organometallic chemistry and catalyst discovery programs within academic and industrial laboratories.
• In the synthesis of advanced materials and specialty polymers where precise catalytic control is required.

Basic Information

Product Name	2-(Di-T-Butylphosphino)Ethylamine, Min. 97% (10 Wt% In Thf)
CAS No.	1053658-84-6
Molecular Formula	C10H24NP
Molecular Weight	189.28 g/mol
Synonyms	2-(Di-tert-Butylphosphino)ethylamine; 2-(Di-t-butylphosphino)ethanamine; N-(2-(Di-tert-butylphosphino)ethyl)amine; Di-tert-butyl(2-aminoethyl)phosphine; Aminoethyldi-tert-butylphosphine; DTBP-EA; (2-Aminoethyl)di-tert-butylphosphine
EINECS	Contact for details

Quality Control

Our 2-(Di-T-Butylphosphino)Ethylamine solution undergoes rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Each batch is analyzed to confirm identity, purity, and solution concentration. Certificates of Analysis (COA) detailing assay (by NMR or titration), solvent content, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (nitrogen or argon) at 2-8°C to minimize oxidation and volatility. The container should be kept in a cool, dry, well-ventilated area away from heat and ignition sources. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (NMR/Titration)	Min. 97% (of 2-(Di-T-Butylphosphino)Ethylamine)
Concentration (in THF)	10 Wt% ± 0.5%
Solvent (THF) Content	Balance
Water Content (KF)	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.