Description

(E)-N'-Benzyl-1-({[(tert-Butoxy)Carbonyl]Amino}Amino)-n-(2,2,2-Trifluoroethyl)Methanimidamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex bioactive molecules. Its value lies in its role as a key building block, enabling the introduction of specific functional groups critical for drug discovery and development. This compound is essential for research and production in the pharmaceutical and agrochemical industries, particularly for medicinal chemists developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Synthesis: Serves as a precursor for developing advanced crop protection agents and herbicides.
• Peptidomimetic Development: Employed in the design and synthesis of peptide analogs and mimetics with enhanced stability and bioavailability.
• Chemical Biology Probes: Utilized to create specialized molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	(E)-N'-Benzyl-1-({[(tert-Butoxy)Carbonyl]Amino}Amino)-n-(2,2,2-Trifluoroethyl)Methanimidamide
CAS No.	1053657-16-1
Molecular Formula	C16H21F3N4O2
Molecular Weight	358.36 g/mol
Synonyms	(E)-N'-Benzyl-1-((tert-butoxycarbonyl)amino)-N-(2,2,2-trifluoroethyl)formamidine; Boc-protected Trifluoroethyl-Benzyl Formamidine; tert-Butyl (E)-((benzylamino)((2,2,2-trifluoroethyl)amino)methylene)carbamate; 1-((tert-Butoxycarbonyl)amino)-N'-benzyl-N-(2,2,2-trifluoroethyl)methanimidamide; N'-Benzyl-N-(2,2,2-trifluoroethyl)-1-((tert-butoxycarbonyl)amino)methanimidamide; CAS 1053657-16-1
EINECS	Contact for details

Quality Control

Our (E)-N'-Benzyl-1-({[(tert-Butoxy)Carbonyl]Amino}Amino)-n-(2,2,2-Trifluoroethyl)Methanimidamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.