Description

tert-Butyl Azetidin-3-Ylmethyl(Methyl)Carbamate is a high-purity, protected azetidine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A versatile synthon for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce the azetidine moiety, a valuable pharmacophore that can modulate the biological activity and metabolic profile of lead compounds.
• Protease Inhibitor Research: Serves as a precursor in the development of inhibitors for various enzymes, including proteases and kinases.
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides where the azetidine ring contributes to biological efficacy.
• Ligand and Catalyst Development: Used to create novel chiral ligands and organocatalysts for stereoselective transformations.
• Chemical Biology Probes: Acts as a starting material for the synthesis of molecular probes used to study biological pathways and protein function.

Basic Information

Product Name	tert-Butyl Azetidin-3-Ylmethyl(Methyl)Carbamate
CAS No.	1053655-53-0
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1,1-Dimethylethyl 3-[(Methylamino)methyl]azetidine-1-carboxylate; tert-Butyl 3-[(Methylamino)methyl]azetidine-1-carboxylate; N-Methyl-1-(tert-butoxycarbonyl)azetidine-3-methanamine; (Azetidin-3-ylmethyl)methylcarbamic acid tert-butyl ester; 3-[(Methylamino)methyl]-1-azetidinecarboxylic acid 1,1-dimethylethyl ester; BOC-Azetidine-3-yl-N-methylamine; tert-Butyl N-methyl-N-(azetidin-3-ylmethyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl Azetidin-3-Ylmethyl(Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.