Description

D,L-7-Aza-3-Indolylglycine is a non-natural amino acid derivative featuring an aza-indole core structure, which is of significant interest in advanced chemical synthesis and pharmaceutical research. This compound serves as a versatile and valuable building block for the development of novel bioactive molecules, including peptide mimetics and enzyme inhibitors. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting various diseases.
• Peptidomimetic Research: Used to incorporate the unique aza-indole moiety into peptide backbones to enhance metabolic stability and binding affinity.
• Medicinal Chemistry: Serves as a crucial scaffold for constructing libraries of small molecules for high-throughput screening (HTS).
• Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) or other targeted therapeutic agents.
• Chemical Biology Probes: Employed in the design of probes to study enzyme function and protein-protein interactions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	D,L-7-Aza-3-Indolylglycine
CAS No.	1052209-51-4
Molecular Formula	C10H9N3O2
Molecular Weight	203.20 g/mol
Synonyms	7-Azaindole-3-glycine; 3-(7-Aza-1H-indol-3-yl)-2-aminopropanoic acid; DL-7-Azaindol-3-ylglycine; 2-Amino-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid; 7-Aza-Trp; 7-Azatryptophan (DL-form); (RS)-2-Amino-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid; 7-AIA
EINECS	Contact for details

Quality Control

Our D,L-7-Aza-3-Indolylglycine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.