Description

2-Hydroxy-2-Methylpropanethioamide is a specialized thiocarbonyl compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique structure, featuring both hydroxyl and thioamide functional groups, makes it a valuable building block for constructing complex molecules and heterocyclic systems. This high-purity intermediate is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing sulfur heterocycles or thioamide functionalities.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-Hydroxy-2-Methylpropanethioamide
CAS No.	1051463-20-7
Molecular Formula	C4H9NOS
Molecular Weight	119.18 g/mol
Synonyms	2-Hydroxy-2-methylpropane-1-thioamide; 2-Hydroxy-2-methylpropanethioamide; 2-Methyl-2-hydroxypropanethioamide; α-Hydroxyisobutyrothioamide; 1-Hydroxy-2-methyl-2-propanethioamide; Isobutyrothioamide, α-hydroxy-; 2-Hydroxyisobutyrothioamide
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-Methylpropanethioamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.