Description

(R)-3-Carbamoyl-Piperidine-1-Carboxylic Acid Benzyl Ester CAS NO 1050446-94-0 is a high-purity chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The piperidine-carbamoyl structure makes it valuable for constructing peptidomimetic scaffolds in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high stereochemical purity and reliable supply.
• Academic & R&D Laboratories: Used in exploratory chemistry for developing new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	(R)-3-Carbamoyl-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	1050446-94-0
Molecular Formula	C14H18N2O3
Molecular Weight	262.31 g/mol
Synonyms	Benzyl (R)-3-carbamoylpiperidine-1-carboxylate; (R)-1-(Benzyloxycarbonyl)-3-carbamoylpiperidine; (R)-1-CBZ-3-Carbamoylpiperidine; (R)-3-Carbamoyl-1-N-CBZ-piperidine; (R)-N-CBZ-3-Piperidinecarboxamide; (R)-Piperidine-3-carboxamide, 1-[(benzyloxy)carbonyl]-; (3R)-1-[(Benzyloxy)carbonyl]piperidine-3-carboxamide
EINECS	Contact for details

Quality Control

Our (R)-3-Carbamoyl-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.