Description

1-Bromo-4-Methoxy-2-Trifluoromethoxy-Benzene is a high-value, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is engineered to provide a unique combination of bromine and trifluoromethoxy substituents, offering versatile reactivity for constructing complex molecular architectures. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific halogenated and fluorinated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules with potential CNS, anti-inflammatory, or anti-infective properties.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of advanced electronic materials for displays and organic light-emitting diodes, leveraging its aromatic core and halogen functionality.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig couplings for carbon-carbon and carbon-heteroatom bond formation.
• Fluorine Chemistry Research: An important compound for studying the effects of the trifluoromethoxy group on physicochemical properties like lipophilicity, metabolic stability, and bioavailability.
• Polymer & Resin Modifier: Can be incorporated as a monomer or additive to impart specific properties like flame retardancy or altered solubility to specialty polymers.

Basic Information

Product Name	1-Bromo-4-Methoxy-2-Trifluoromethoxy-Benzene
CAS No.	1049730-84-8
Molecular Formula	C8H6BrF3O2
Molecular Weight	271.04 g/mol
Synonyms	4-Bromo-1-methoxy-2-(trifluoromethoxy)benzene; 2-Bromo-5-methoxy-1-(trifluoromethoxy)benzene; 1-Bromo-4-methoxy-2-(trifluoromethoxy)benzene; Benzene, 1-bromo-4-methoxy-2-(trifluoromethoxy)-; 4-Methoxy-2-(trifluoromethoxy)bromobenzene; 2-Trifluoromethoxy-4-methoxybromobenzene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request. Our quality management system supports cGMP and ISO standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.