Description

Catasium(R) Mnxyl(R), 3,4-Bis[(2R,5R)-2,5-Dimethylphospholanyl]-1-(3,5-Dimethylphenyl)-1H-Pyrrol-2,5-Dione is a highly specialized, chiral phosphine ligand designed for advanced asymmetric catalysis. This compound matters because it enables the precise control of stereochemistry in critical synthetic transformations, offering researchers and manufacturers a powerful tool to create enantiomerically pure intermediates and active pharmaceutical ingredients (APIs). Industries involved in fine chemical synthesis, pharmaceutical development, and advanced material science require this ligand for its ability to impart high enantioselectivity and catalytic efficiency in challenging reactions like hydrogenations and cross-couplings.

Application

• As a key chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure pharmaceutical intermediates.
• Utilized in asymmetric cross-coupling catalysis for constructing complex, chiral carbon-carbon and carbon-heteroatom bonds.
• Enabling stereoselective synthesis in the research and development of new APIs and agrochemicals.
• Critical component in homogeneous catalyst systems for the fine chemical and specialty materials industries.
• Used in academic and industrial R&D to explore novel catalytic methodologies and reaction pathways.
• Potential application in the synthesis of chiral ligands and organocatalysts for further catalytic applications.

Basic Information

Product Name	Catasium(R) Mnxyl(R), 3,4-Bis[(2R,5R)-2,5-Dimethylphospholanyl]-1-(3,5-Dimethylphenyl)-1H-Pyrrol-2,5-Dione
CAS No.	1044553-58-3
Molecular Formula	C26H39N1O2P2
Molecular Weight	459.55 g/mol
Synonyms	3,4-Bis[(2R,5R)-2,5-Dimethylphospholanyl]-1-(3,5-dimethylphenyl)-1H-pyrrole-2,5-dione; (2R,5R)-2,5-Dimethylphospholane-based Pyrrolidine Dione Ligand; Catasium Mnxyl Ligand; Chiral Bis(phospholane) Ligand; Asymmetric Hydrogenation Ligand; (R,R)-DMPP-based Ligand; 1-(3,5-Dimethylphenyl)-3,4-bis[(2R,5R)-2,5-dimethylphospholanyl]-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our Catasium(R) Mnxyl(R) ligand is produced under stringent quality control protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and NMR for structural verification. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical specifications. Our quality management system supports compliance with cGMP standards for applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.