Description

2-{2-[(2R,5R)-2,5-Dimethyl-1-Phospholano]Phenyl}1,3-Dioxolane, Min. 97% is a high-purity, chiral phosphine ligand with a dioxolane-protected aldehyde functionality. This compound is critical for enabling highly selective and efficient catalytic transformations in asymmetric synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel chiral active ingredients.

Application

• Asymmetric Hydrogenation Catalyst Ligand: A key component in chiral catalysts for the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Used in the synthesis of complex, single-enantiomer drug molecules, including active pharmaceutical ingredients (APIs).
• Agrochemical Product Development: Facilitates the creation of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical and Specialty Chemical Production: Enables the manufacture of high-value chiral flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: Serves as a versatile tool for methodological development in organic and organometallic chemistry research.
• Cross-Coupling Reaction Ligand: Can be employed to modify metal catalysts for asymmetric C-C and C-X bond-forming reactions.

Basic Information

Item	Details
Product Name	2-{2-[(2R,5R)-2,5-Dimethyl-1-Phospholano]Phenyl}1,3-Dioxolane, Min. 97%
CAS No.	1044256-04-3
Molecular Formula	C15H21O2P
Molecular Weight	264.30 g/mol
Synonyms	(2R,5R)-2,5-Dimethyl-1-(2-(1,3-dioxolan-2-yl)phenyl)phospholane; (R,R)-2,5-Dimethyl-1-(2-(1,3-dioxolan-2-yl)phenyl)phospholane; Dioxolane-Protected Josiphos-Type Ligand; Chiral Dioxolanylphenylphospholane Ligand; (R,R)-DMPP-Dioxolane; (2R,5R)-DMPP-Dioxolane; 2-(2-((2R,5R)-2,5-Dimethylphospholan-1-yl)phenyl)-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available upon request, detailing results from HPLC, NMR, and other analytical methods to guarantee the minimum 97% purity and correct stereochemistry.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.