Description

(±)-Tolterodine-D14 Tartrate [N,n-Di(iso-Propyl-D7)] is a high-purity, stable isotope-labeled internal standard critical for ensuring the accuracy and reliability of quantitative bioanalytical methods. This deuterated compound is essential for precise pharmacokinetic and metabolic studies, providing unmatched specificity by eliminating interference from endogenous compounds or the parent drug. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in method development and validation for the antimuscarinic drug tolterodine.

Application

• Primary use as an Internal Standard (IS) in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and Gas Chromatography-Mass Spectrometry (GC-MS) bioanalysis.
• Quantification of tolterodine and its metabolites in complex biological matrices such as plasma, serum, and urine for pharmacokinetic (PK) studies.
• Method development and validation in support of regulatory submissions (e.g., FDA, EMA) for drug approval and bioequivalence studies.
• High-sensitivity applications in doping control and forensic toxicology to detect and quantify tolterodine.
• Use in stable isotope dilution assays to achieve the highest level of accuracy in mass spectrometry-based quantification.
• Research into the metabolic pathways and disposition of tolterodine within the body.

Basic Information

Item	Detail
Product Name	(±)-Tolterodine-D14 Tartrate [N,n-Di(iso-Propyl-D7)]
CAS No.	1043911-42-7
Molecular Formula	C26H30D14NO7
Molecular Weight	Approx. 520.7 g/mol
Synonyms	Tolterodine-d14 Tartrate; Tolterodine (N,N-diisopropyl-d7) Tartrate; 2-[(1R)-3-[Bis(1-methylethyl-d7)amino]-1-phenylpropyl]-4-methylphenol-d7 Tartrate; Deuterated Tolterodine Tartrate; Tolterodine-D14 L-Tartrate; Isotopically Labeled Tolterodine; [2H14]-Tolterodine Tartrate; Internal Standard for Tolterodine Assay
EINECS	Contact for details

Quality Control

Every batch of our (±)-Tolterodine-D14 Tartrate is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, verified by advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing assay, isotopic enrichment (D14), and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for regulated bioanalysis and research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D14)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.