Description

S-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene]-2,2'-Diol is a high-purity, chiral binaphthol derivative, a crucial class of compounds in asymmetric synthesis. Its value lies in its role as a privileged ligand and catalyst precursor, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, including hydrogenation, coupling, and cycloaddition.
• As a catalyst precursor for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and intermediates.
• In the development of chiral stationary phases (CSPs) for analytical and preparative chromatography.
• As a building block for constructing sophisticated chiral molecular frameworks and macrocycles.
• For research in asymmetric organocatalysis and the study of chiral induction mechanisms.
• In the synthesis of advanced optical materials and liquid crystals where specific chirality is required.

Basic Information

Product Name	S-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene]-2,2'-Diol
CAS No.	1041858-16-5
Molecular Formula	C40H34O2
Molecular Weight	546.70 g/mol
Synonyms	(S)-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene-2,2'-diol; (S)-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Bi-2-naphthol; (S)-3,3'-Bis(2,4,6-Trimethylphenyl)-BINOL; (S)-3,3'-Bis(2,4,6-Trimethylphenyl)-2,2'-Dihydroxy-1,1'-binaphthyl; (S)-3,3'-Di(2,4,6-Trimethylphenyl)-BINOL; (S)-3,3'-Di(2,4,6-Trimethylphenyl)-1,1'-Bi-2-naphthol; (S)-3,3'-Di(2,4,6-Trimethylphenyl)-2,2'-Dihydroxy-1,1'-binaphthyl; S-3,3'-Bis(2,4,6-Trimethylphenyl)-BINOL
EINECS	Contact for details

Quality Control

Our S-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene]-2,2'-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for chiral auxiliaries in pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.