Description

[6-(Trimethylammonium)Hexyl] Methanethiosulfonate Bromide is a specialized, high-purity chemical reagent featuring a reactive methanethiosulfonate (MTS) group linked to a cationic trimethylammonium tail. This compound matters for its role as a versatile bioconjugation and site-directed spin labeling agent, enabling precise covalent modifications of cysteine residues in proteins and peptides. Researchers and process developers in the pharmaceutical, biotechnology, and life sciences sectors need it for advanced applications in structural biology, drug discovery, and the development of diagnostic assays.

Application

• Site-Directed Spin Labeling (SDSL) in Electron Paramagnetic Resonance (EPR) spectroscopy for studying protein dynamics and structure.
• Bioconjugation and Protein Labeling, specifically for introducing functional groups, fluorophores, or other probes onto cysteine residues.
• Structural Biology Research, including the mapping of protein-protein interactions and conformational changes.
• Development of Diagnostic Reagents and biosensors that require stable, site-specific attachment of signaling molecules.
• Cross-linking Agent for studying protein folding, stability, and oligomerization states.
• Chemical Biology Tool for creating chemically modified proteins with tailored properties for therapeutic or analytical purposes.

Basic Information

Product Name	[6-(Trimethylammonium)Hexyl] Methanethiosulfonate Bromide
CAS No.	1041424-77-4
Molecular Formula	C10H22BrNO2S2
Molecular Weight	324.32 g/mol
Synonyms	(6-Trimethylammoniumhexyl) Methanethiosulfonate Bromide; MTSL Hexylammonium Bromide; 1-(6-(Trimethylammonio)hexyl) methanethiosulfonate bromide; MTSSL Hexyl TMA; (6-(Trimethylazaniumyl)hexyl) methanesulfonothioate bromide; Thiol-reactive spin label; MTS reagent; Protein cysteine modification reagent
EINECS	Contact for details

Quality Control

Our [6-(Trimethylammonium)Hexyl] Methanethiosulfonate Bromide is manufactured under strict quality protocols to ensure the high purity and consistency required for sensitive research applications. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in water, DMSO, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.