Description

2-Amino-5-Fluorobenzeneboronic Acid is a high-value boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both an amino and a boronic acid functional group on a fluorinated benzene ring, makes it an indispensable reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds with potential therapeutic activity.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require fluorinated aromatic structures.
• Material Science: Serves as a monomer or linker in the synthesis of organic electronic materials, such as polymers for OLEDs or sensors.
• Chemical Biology & Proteomics: Utilized in the development of enzyme inhibitors, molecular probes, and affinity ligands due to its boronic acid moiety's ability to bind diols.
• Academic & Contract Research: Essential for methodological development in organic synthesis and catalysis research within university and CRO laboratories.
• Liquid Crystal & Dye Synthesis: Acts as a building block for creating fluorinated aromatic cores in advanced functional dyes and liquid crystal materials.

Basic Information

Product Name	2-Amino-5-Fluorobenzeneboronic Acid
CAS No.	1040400-87-0
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(2-Amino-5-fluorophenyl)boronic acid; 5-Fluoro-2-aminophenylboronic acid; 2-Amino-5-fluorobenzeneboronic acid pinacol ester (common derivative); 2-Amino-5-fluorophenyl-B(OH)2; 5-Fluoroanthranilic acid boronic acid; Boronic acid, B-(2-amino-5-fluorophenyl)-; 2-NH2-5-F-C6H3B(OH)2
EINECS	Contact for details

Quality Control

Every batch of our 2-Amino-5-Fluorobenzeneboronic Acid is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive applications like pharmaceutical R&D. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.