Description

3-Amino-Tetrahydrofuran-3-Carbonitrile is a versatile heterocyclic building block featuring both amino and nitrile functional groups on a tetrahydrofuran scaffold. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for creating fused ring systems and chiral compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the tetrahydrofuran ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex fine chemicals and specialty materials requiring specific stereochemistry.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic synthesis, including ring-opening and functional group transformation reactions.

Basic Information

Product Name	3-Amino-Tetrahydrofuran-3-Carbonitrile
CAS No.	1037301-15-7
Molecular Formula	C5H8N2O
Molecular Weight	112.13 g/mol
Synonyms	3-Aminotetrahydrofuran-3-carbonitrile; 3-Aminooxolane-3-carbonitrile; 3-Cyano-3-aminotetrahydrofuran; Tetrahydro-3-amino-3-furancarbonitrile; 3-Amino-3-cyanotetrahydrofuran; 3-Aminotetrahydro-3-furancarbonitrile; 3-Furancarbonitrile, 3-amino-tetrahydro-; 1037301-15-7
EINECS	Contact for details

Quality Control

Our 3-Amino-Tetrahydrofuran-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.