Description

1-(4-Cyanophenyl)-N,n-Dimethylmethanesulfonamide is a specialized organic sulfonamide derivative featuring a cyano-substituted phenyl ring, serving as a valuable synthetic intermediate in advanced chemical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for use in medicinal chemistry, catalyst ligand synthesis, and as a key building block for novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its sulfonamide and nitrile functional groups.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing molecular probes.
• Catalyst & Ligand Synthesis: The dimethylamino and sulfonamide groups make it a potential precursor for creating novel ligands in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Item	Detail
Product Name	1-(4-Cyanophenyl)-N,n-Dimethylmethanesulfonamide
CAS No.	1036479-03-4
Molecular Formula	C10H12N2O2S
Molecular Weight	224.28 g/mol
Synonyms	N,N-Dimethyl-1-(4-cyanophenyl)methanesulfonamide; 4-[(Dimethylsulfamoyl)methyl]benzonitrile; 1-(4-Cyanobenzyl)-N,N-dimethylsulfonamide; p-Cyanobenzyl dimethylsulfamoyl; Benzonitrile, 4-[(dimethylsulfamoyl)methyl]-; (4-Cyanophenyl)methanesulfonamide, N,N-dimethyl-
EINECS	Contact for details

Quality Control

Our 1-(4-Cyanophenyl)-N,n-Dimethylmethanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.