Description

Methyl (2,3-Difluorophenyl)Acetate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on new active ingredients, where the introduction of fluorine atoms is critical for modulating biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where fluorination enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and hydrolysis to create more complex fluorinated aromatic structures.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in both academic and industrial R&D laboratories.

Basic Information

Product Name	Methyl (2,3-Difluorophenyl)Acetate
CAS No.	1036273-31-0
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	Methyl 2-(2,3-Difluorophenyl)acetate; (2,3-Difluorophenyl)acetic acid methyl ester; 2-(2,3-Difluorophenyl)acetic acid methyl ester; Methyl (2,3-difluorobenzene)acetate; Acetic acid, 2-(2,3-difluorophenyl)-, methyl ester; Methyl α-(2,3-difluorophenyl)acetate
EINECS	Contact for details

Quality Control

Our Methyl (2,3-Difluorophenyl)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically exceeding 97% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for research and development under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.