Description

(2,4,5-Trifluorophenyl)Acetic Acid Methyl Ester is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the (2,4,5-trifluorophenyl) moiety into complex molecular architectures, enabling precise structural modifications. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where its unique fluorine substitution pattern is leveraged to fine-tune the biological activity and physical properties of target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components in electronic display technologies and organic light-emitting diodes.
• Advanced Polymer Chemistry: Incorporated into specialty polymers and coatings to impart specific chemical resistance, thermal stability, or surface properties.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
• Fluorine Chemistry Studies: Used as a model compound or intermediate in academic and industrial research focused on fluorination reactions and aromatic substitution patterns.

Basic Information

Product Name	(2,4,5-Trifluorophenyl)Acetic Acid Methyl Ester
CAS No.	1036273-20-7
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	Methyl (2,4,5-Trifluorophenyl)acetate; 2-(2,4,5-Trifluorophenyl)acetic Acid Methyl Ester; Methyl 2-(2,4,5-Trifluorophenyl)acetate; (2,4,5-Trifluorobenzene)acetic Acid Methyl Ester; Methyl 2,4,5-Trifluorophenylacetate; 1036273-20-7; Methyl (2,4,5-Trifluorobenzene)acetate
EINECS	Contact for details

Quality Control

Our (2,4,5-Trifluorophenyl)Acetic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.