Description

3-(Boc-Aminomethyl)-4-Fluorobenzeneboronic Acid Pinacol Ester, 96% is a high-purity, protected boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Key intermediate in Suzuki-Miyaura cross-coupling reactions for biaryl bond formation.
• Building block for the synthesis of fluorinated pharmaceutical candidates, leveraging the fluorine atom for metabolic stability and bioavailability.
• Precursor in the development of protease inhibitors and other enzyme-targeted therapeutics.
• Research chemical for constructing peptidomimetics and other bioactive scaffolds containing an aminomethyl group.
• Starting material in agrochemical research for creating novel herbicides or fungicides.
• Used in material science for the synthesis of functionalized organic ligands and monomers.

Basic Information

Product Name	3-(Boc-Aminomethyl)-4-Fluorobenzeneboronic Acid Pinacol Ester, 96%
CAS No.	1035391-48-0
Molecular Formula	C₁₈H₂₇BFNO₄
Molecular Weight	351.23 g/mol
Synonyms	4-Fluoro-3-((tert-butoxycarbonylamino)methyl)benzeneboronic acid pinacol ester; 3-((Boc-amino)methyl)-4-fluorobenzeneboronic acid pinacol ester; 3-(N-Boc-aminomethyl)-4-fluorophenylboronic acid pinacol ester; (3-((tert-Butoxycarbonylamino)methyl)-4-fluorophenyl)boronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[3-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-4-fluorophenyl]-4,4,5,5-tetramethyl-; BOC-AMINOMETHYL-4-FLUOROBENZENEBORONIC ACID PINACOL ESTER; tert-Butyl N-[[4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]carbamate
EINECS	Contact for details

Quality Control

Our 3-(Boc-Aminomethyl)-4-Fluorobenzeneboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.