Description

Methyl 2-(4-Chloro-3-Fluorophenyl)Acetate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its core value lies in its versatile chemical structure, which serves as a key intermediate for constructing more complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated phenyl moiety.
• Liquid Crystal Material Precursor: Serves as a starting material for the synthesis of fluorinated aromatic compounds used in electronic display technologies.
• Organic Ligand Development: Employed in the creation of specialized ligands for catalysis and material science applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP conditions.
• Academic & Industrial Research: A valuable reagent for methodological studies in cross-coupling reactions and ester functionalization chemistry.

Basic Information

Product Name	Methyl 2-(4-Chloro-3-Fluorophenyl)Acetate
CAS No.	1035262-89-5
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Methyl (4-Chloro-3-fluorophenyl)acetate; (4-Chloro-3-fluorophenyl)acetic acid methyl ester; 2-(4-Chloro-3-fluorophenyl)acetic acid methyl ester; Methyl 4-chloro-3-fluorobenzeneacetate; 1035262-89-5; Methyl (4-chloro-3-fluorophenyl)ethanoate; 4-Chloro-3-fluorophenylacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Chloro-3-Fluorophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under ISO and cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.