Description

4-Cyano-2-Fluorobenzeneboronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for modern cross-coupling reactions, enabling the efficient construction of complex fluorinated and cyanated aromatic scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated and cyanated biaryl compounds with potential biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate fluorine and nitrile functional groups for enhanced efficacy and environmental profile.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Chemical Synthesis: Enables the introduction of both fluorine and boronic ester-protected phenyl groups in a single, stable molecule, streamlining multi-step synthetic routes.
• Library Synthesis: Ideal for generating diverse compound libraries in medicinal chemistry for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Cyano-2-Fluorobenzeneboronic Acid, Pinacol Ester
CAS No.	1035235-29-0
Molecular Formula	C13H15BFNO2
Molecular Weight	247.08 g/mol
Synonyms	2-Fluoro-4-cyanophenylboronic acid pinacol ester; 4-Cyano-2-fluorophenylboronic acid pinacol ester; (4-Cyano-2-fluorophenyl)boronic acid pinacol ester; 2-Fluoro-4-cyanobenzene-1-boronic acid pinacol ester; Pinacol (4-cyano-2-fluorophenyl)boronate; 4-CN-2-F-PhBpin; B-(4-Cyano-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-Fluorobenzeneboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.