Description

1H-Pyrazolo[4,3-B]Pyridine-5-Carbonitrile is a high-value heterocyclic organic compound featuring a fused pyrazolopyridine core with a nitrile functional group. This molecular structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry for constructing diverse compound libraries.
• Agrochemical Research: Serves as a core structure for synthesizing new pesticides and herbicides with specific modes of action.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for complex heterocyclic synthesis and methodology development.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	1H-Pyrazolo[4,3-B]Pyridine-5-Carbonitrile
CAS No.	1033772-22-3
Molecular Formula	C7H4N4
Molecular Weight	144.14 g/mol
Synonyms	1H-Pyrazolo[4,3-b]pyridine-5-carbonitrile; 5-Cyano-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine-5-carbonitrile; Pyrazolo[4,3-b]pyridine-5-carbonitrile; 1033772-22-3; 5-CN-1H-Pyrazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazolo[4,3-B]Pyridine-5-Carbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades Available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.