Description

Maraviroc-D6 is a deuterium-labeled analog of the CCR5 antagonist Maraviroc, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity reference material is essential for ensuring accuracy and reliability in pharmacokinetic and metabolic studies, where precise measurement is critical. It is primarily utilized by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical service providers engaged in bioanalytical method development and validation.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in bioanalytical studies.
• Quantitative reference material for pharmacokinetic (PK) and bioavailability research.
• Metabolite identification and profiling in drug metabolism and disposition (DMPK) studies.
• Method development and validation for the quantification of Maraviroc in biological matrices.
• Quality control and assurance in clinical trial sample analysis.
• Stability-indicating assays and impurity profiling in pharmaceutical development.

Basic Information

Product Name	Maraviroc-D6
CAS No.	1033699-22-7
Molecular Formula	C₂₉H₄₅D₆F₂N₅O
Molecular Weight	517.75 g/mol
Synonyms	4,4-Difluoro-N-{(1S)-3-[exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide-d6; UK-427,857-d6; Celsentri-d6; Selzentry-d6; Maraviroc (hexadeuterated); Maraviroc Internal Standard; CCR5 Antagonist-d6
EINECS	Contact for details

Quality Control

Our Maraviroc-D6 is manufactured under strict quality control protocols to ensure the highest standards of purity and isotopic enrichment, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from NMR, HPLC, and MS analysis. We adhere to relevant industry guidelines for reference standards to support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98.0 atom % D
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.