Description

1-(3-Bromo-4-Fluorobenzoyl)Piperidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated benzoylpiperidine structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its halogenated aromatic and piperidine moieties.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific halogenated benzamide derivatives.
• Academic Research: Employed in university and institutional labs for novel heterocyclic chemistry and methodology development.

Basic Information

Product Name	1-(3-Bromo-4-Fluorobenzoyl)Piperidine
CAS No.	1033201-74-9
Molecular Formula	C12H13BrFNO
Molecular Weight	286.14 g/mol
Synonyms	3-Bromo-4-fluoro-N-piperidin-1-ylbenzamide; 1-(3-Bromo-4-fluorobenzoyl)piperidine; (3-Bromo-4-fluorophenyl)(piperidin-1-yl)methanone; Piperidine, 1-(3-bromo-4-fluorobenzoyl)-; 1033201-74-9
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-4-Fluorobenzoyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.