Description

Iododifluoroaceticacid CAS NO 1032021-83-2 is a specialized organofluorine building block featuring both iodine and fluorine substituents on an acetic acid backbone. This unique structure makes it a valuable reagent for introducing the difluoroacetate moiety in advanced synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. Its reactivity is leveraged in the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated analogs of drug candidates to modulate metabolism, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the difluoroacetate group can enhance biological activity.
• Material Science Research: Serves as a precursor for creating fluorinated polymers or surface modifiers with unique properties like chemical resistance or low surface energy.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore the impact of fluorine and iodine substitution on biological targets.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers offering bespoke synthesis services for clients in life sciences.
• Radioactive Tracer Development: The iodine atom provides a potential site for radioiodination (e.g., I-125, I-131) for creating diagnostic imaging agents or research probes.

Basic Information

Product Name	Iododifluoroaceticacid
CAS No.	1032021-83-2
Molecular Formula	C2HF2IO2
Molecular Weight	237.93 g/mol
Synonyms	2-Iodo-2,2-difluoroacetic Acid; Difluoro(iodo)acetic Acid; Iododifluoroethanoic Acid; α,α-Difluoro-α-iodoacetic Acid; Iodo(difluoro)acetic Acid; Iododifluoro Acetic Acid; 1032021-83-2; Acetic acid, 2-iodo-2,2-difluoro-
EINECS	Contact for details

Quality Control

Our Iododifluoroaceticacid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. While produced to meet high-purity standards for laboratory and pilot-scale use, specific grade requirements (e.g., for GMP applications) can be discussed and tailored upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. Ensure containers are kept tightly sealed when not in use to prevent moisture absorption or degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.