Description

2-Bromo-3-Chlorobenzonitrile is a versatile halogenated benzonitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its dual halogen functionality, which allows for selective cross-coupling reactions and further functionalization to build complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a halogenated aromatic core for further modification.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the benzonitrile moiety is a common structural feature.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of bromine and chlorine substituents.
• Chemical Biology & Proteomics: Utilized as a molecular scaffold or tagging reagent in the design of chemical probes and enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Bromo-3-Chlorobenzonitrile
CAS No.	1031929-33-5
Molecular Formula	C7H3BrClN
Molecular Weight	216.46 g/mol
Synonyms	3-Chloro-2-bromobenzonitrile; 2-Bromo-3-chlorobenzene carbonitrile; Benzonitrile, 2-bromo-3-chloro-; 2-Bromo-3-chloro-benzonitrile; (2-Bromo-3-chlorophenyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chlorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards. Our commitment to cGMP principles and rigorous quality control ensures a reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.