Description

Ceftobiprole Trifluoroacetate is a trifluoroacetate salt form of the advanced-generation cephalosporin antibiotic, ceftobiprole. This high-purity intermediate is critical for the research and development of novel antibacterial agents targeting resistant Gram-positive pathogens, including methicillin-resistant *Staphylococcus aureus* (MRSA). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and API manufacturers engaged in developing next-generation anti-infective therapies.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in antibiotic manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the production of the final ceftobiprole API for clinical and commercial use.
• Antimicrobial Research: Used in in vitro studies to investigate mechanisms of action, resistance patterns, and efficacy against multidrug-resistant bacterial strains.
• Formulation Development: Employed in pre-formulation and stability studies for developing injectable antibiotic formulations.
• Regulatory Submissions: Provides essential material for generating impurity profiles and stability data required for regulatory filings (e.g., FDA, EMA).

Basic Information

Product Name	Ceftobiprole Trifluoroacetate
CAS No.	1031275-04-3
Molecular Formula	C26H25F3N8O10S2
Molecular Weight	746.65 g/mol
Synonyms	Ceftobiprole TFA Salt; (6R,7R)-7-[(2Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetamido]-3-[(3R,4R)-4-[(3-carbamoylpyridin-1-ium-1-yl)methyl]-3-hydroxypyrrolidin-1-ium-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate; Ceftobiprole Medocaril Trifluoroacetate Impurity; BAL5788 Trifluoroacetate; Zevtera Impurity
EINECS	Contact for details

Quality Control

Our Ceftobiprole Trifluoroacetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) that detail all testing results, meeting the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%
Microbial Enumeration	Meets Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.