Description

Carbamic Acid, n-[(1R,2R)-2-(Aminomethyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester, Rel(Racemic) is a specialized chiral intermediate featuring a protected amine and carbamate functional group. This compound is of significant value in pharmaceutical research and development, particularly for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs).
• Protease Inhibitor Development: Used in research for creating inhibitors targeting specific enzymes.
• Peptidomimetic Chemistry: Serves as a constrained scaffold in the design of peptide-like compounds with enhanced metabolic stability.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce the (1R,2R)-2-(aminomethyl)cyclohexyl moiety.
• Medicinal Chemistry Research: Utilized in lead optimization and structure-activity relationship (SAR) studies.
• Boc-Protected Amine Precursor: The tert-butyloxycarbonyl (Boc) group provides a versatile protecting strategy for primary amines in multi-step syntheses.

Basic Information

Item	Detail
Product Name	Carbamic Acid, n-[(1R,2R)-2-(Aminomethyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester, Rel(Racemic)
CAS No.	1030390-99-8
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	(1R,2R)-2-((((tert-Butoxycarbonyl)amino)methyl)cyclohexanamine (racemic); (1R*,2R*)-2-((((tert-Butoxycarbonyl)amino)methyl)cyclohexanamine; tert-Butyl N-[(1R,2R)-2-(aminomethyl)cyclohexyl]carbamate (racemate); Boc-ACHC-NH2 (racemic); (1R,2R)-2-(Aminomethyl)cyclohexylcarbamic acid tert-butyl ester (racemic); trans-2-((Boc-amino)methyl)cyclohexylamine (racemic mixture); N-Boc-trans-1,2-cyclohexanediamine (isomer); 1030390-99-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for each lot are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for the (1R,2R) isomer pair)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.