Description

4-(3,5-Difluorophenoxy)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex biaryl or heterobiaryl motifs for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated phenoxy architectures.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors for biochemical research and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	4-(3,5-Difluorophenoxy)Phenylboronic Acid
CAS No.	1029438-51-4
Molecular Formula	C12H9BF2O3
Molecular Weight	250.01 g/mol
Synonyms	[4-(3,5-Difluorophenoxy)phenyl]boronic acid; 4-(3,5-Difluorophenoxy)benzeneboronic acid; (4-(3,5-Difluorophenoxy)phenyl)boronic acid; B-[4-(3,5-Difluorophenoxy)phenyl]boronic acid; 1029438-51-4; AKOS025311319; AS-80511; FT-0773297; BDBM50415353; 4-(3,5-Difluorophenoxy)phenylboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 4-(3,5-Difluorophenoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.