Description

tert-Butyl n-[1-(2-Hydroxyethyl)Cyclobutyl]Carbamate is a specialized carbamate derivative featuring a cyclobutyl ring and a hydroxyethyl side chain, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), where it is used to introduce and protect key functional groups during multi-step synthetic sequences.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Peptidomimetics Research: Used to construct non-peptide scaffolds that mimic the structure and function of peptides for drug discovery.
• Prodrug Development: Serves as a precursor for prodrug strategies, where the carbamate and hydroxyl functionalities can be modified to enhance bioavailability.
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and biological pathways.
• Agrochemical Synthesis: Acts as an intermediate in the development of new, high-performance crop protection agents.
• Polymer Science: Can be utilized as a monomer or chain extender in the synthesis of specialty polyurethanes and polycarbonates with unique properties.

Basic Information

Product Name	tert-Butyl n-[1-(2-Hydroxyethyl)Cyclobutyl]Carbamate
CAS No.	1028266-97-8
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	1-(2-Hydroxyethyl)cyclobutanamine, N-Boc derivative; tert-Butyl [1-(2-hydroxyethyl)cyclobutyl]carbamate; N-Boc-1-(2-hydroxyethyl)cyclobutanamine; 1-(2-Hydroxyethyl)cyclobutanamine, N-(tert-butoxycarbonyl)-; BOC-1-(2-Hydroxyethyl)cyclobutanamine; Carbamic acid, N-[1-(2-hydroxyethyl)cyclobutyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[1-(2-Hydroxyethyl)Cyclobutyl]Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis, in line with ICH guidelines. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.