Description

1-Fluoro-2-Iodo-4-Methoxybenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the precise introduction of fluorine and iodine substituents into complex molecular architectures. Pharmaceutical, agrochemical, and materials science R&D teams need it for developing new active ingredients and functional materials, leveraging its unique reactivity profile.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the fluorine and iodine atoms can enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced functional molecules used in electronic displays and optoelectronic devices.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings, facilitating carbon-carbon bond formation.
• Fluorine Chemistry Research: Essential for studying the effects of fluorine substitution on aromatic systems in academic and industrial research settings.
• Chemical Labeling & Probe Development: The iodine atom provides a handle for further functionalization or radiolabeling (with I-125) for diagnostic and research applications.

Basic Information

Product Name	1-Fluoro-2-Iodo-4-Methoxybenzene
CAS No.	1028263-94-6
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	2-Fluoro-1-Iodo-4-Methoxybenzene; 4-Methoxy-2-fluoro-1-iodobenzene; 2-Fluoro-4-methoxyiodobenzene; 1-Iodo-2-fluoro-4-methoxybenzene; 4-Methoxy-2-fluorophenyl iodide; 2-Fluoro-4-methoxyphenyl iodide; 2-Fluoro-4-methoxy-1-iodobenzene; 4-Methoxy-2-fluoroiodobenzene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2-Iodo-4-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.