Description

Difluoro-(4-Isopropylphenyl)Acetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the difluoroacetic acid moiety can significantly influence biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where fluorine atoms enhance efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a starting material for creating novel fluorinated ligands used in asymmetric catalysis and material science.
• Advanced Material Precursor: Employed in the synthesis of fluorinated monomers for specialty polymers with enhanced chemical resistance and thermal stability.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.

Basic Information

Product Name	Difluoro-(4-Isopropylphenyl)Acetic Acid
CAS No.	1027514-26-6
Molecular Formula	C11H12F2O2
Molecular Weight	214.21 g/mol
Synonyms	2,2-Difluoro-2-(4-isopropylphenyl)acetic acid; α,α-Difluoro-4-isopropylphenylacetic acid; 4-Isopropyl-α,α-difluorophenylacetic acid; (4-Isopropylphenyl)difluoroacetic acid; 2-(4-Isopropylphenyl)-2,2-difluoroacetic acid; 4-(1-Methylethyl)-α,α-difluorobenzenecetic acid; p-Isopropyl-α,α-difluorophenylacetic acid
EINECS	Contact for details

Quality Control

Our Difluoro-(4-Isopropylphenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.