Description

2,2-Difluoro-2-(3-Chloro-4-Fluorophenyl)Acetic Acid is a specialized fluorinated and chlorinated aromatic acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoroacetic acid moiety can enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the creation of specialty polymers with specific chemical resistance or surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel fluorinated compounds.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise halogenated aromatic structures.

Basic Information

Item	Detail
Product Name	2,2-Difluoro-2-(3-Chloro-4-Fluorophenyl)Acetic Acid
CAS No.	1027514-19-7
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	3-Chloro-4-fluorophenyl(difluoro)acetic acid; (3-Chloro-4-fluorophenyl)difluoroacetic acid; α,α-Difluoro-3-chloro-4-fluorophenylacetic acid; 2,2-Difluoro-2-(3-chloro-4-fluorophenyl)ethanoic acid; Difluoro(3-chloro-4-fluorophenyl)acetic acid; 1027514-19-7; (3-Chloro-4-fluorophenyl)-difluoro-acetic acid
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(3-Chloro-4-Fluorophenyl)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.