Description

Ethyl-2,2-Difluoro-2-(3,4-Dimethylphenyl)Acetate is a high-value fluorinated organic intermediate characterized by its difluoroacetate ester and dimethylphenyl functional groups. This compound is critical for introducing the difluoroacetate moiety into complex molecules, enabling the fine-tuning of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a specialized monomer or intermediate in the production of advanced electronic display materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex fluorinated molecules via esterification and cross-coupling reactions.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of novel, high-value aromatic compounds for specialty chemical applications.

Basic Information

Product Name	Ethyl-2,2-Difluoro-2-(3,4-Dimethylphenyl)Acetate
CAS No.	1027514-17-5
Molecular Formula	C₁₂H₁₄F₂O₂
Molecular Weight	228.24 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(3,4-dimethylphenyl)acetate; 2,2-Difluoro-2-(3,4-dimethylphenyl)acetic Acid Ethyl Ester; Acetic acid, 2,2-difluoro-2-(3,4-dimethylphenyl)-, ethyl ester; Ethyl α,α-Difluoro-3,4-dimethylphenylacetate; 3,4-Dimethyl-α,α-difluorobenzeneacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl-2,2-Difluoro-2-(3,4-Dimethylphenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.