Description

2,2-Difluoro-2-(3-Methoxyphenyl)Acetic Acid is a specialized fluorinated aromatic acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoroacetate moiety adjacent to an aromatic ring, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, especially in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create polymers with enhanced chemical resistance and thermal stability.
• Organic Synthesis Reagent: A versatile reagent for introducing the difluoroacetic acid group into complex molecules under controlled conditions.
• Chemical Research & Development: Fundamental material for exploring new fluorination reactions and building block chemistry in academic and industrial R&D labs.

Basic Information

Product Name	2,2-Difluoro-2-(3-Methoxyphenyl)Acetic Acid
CAS No.	1027513-99-0
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	3-Methoxy-α,α-difluorobenzeneacetic Acid; 2,2-Difluoro-2-(3-methoxyphenyl)ethanoic Acid; (3-Methoxyphenyl)difluoroacetic Acid; α,α-Difluoro-3-methoxybenzeneacetic Acid; 2-(3-Methoxyphenyl)-2,2-difluoroacetic Acid; Difluoro(3-methoxyphenyl)acetic Acid
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(3-Methoxyphenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from incompatible materials such as strong bases and oxidizing agents. Ensure the container is kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.