Description

2,2-Difluoro-2-(4-Methoxyphenyl)Acetic Acid is a high-purity fluorinated aromatic acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethylenecarboxylic acid moiety, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the difluoroacetic acid group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated organic electronic materials, contributing to improved performance in display technologies.
• Advanced Polymer Modification: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Chemical Biology & Probe Development: Utilized in the design of molecular probes and enzyme inhibitors for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom chemical synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Item	Details
Product Name	2,2-Difluoro-2-(4-Methoxyphenyl)Acetic Acid
CAS No.	1027513-97-8
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	4-Methoxy-α,α-difluorophenylacetic Acid; (4-Methoxyphenyl)difluoroacetic Acid; 2,2-Difluoro-2-(4-methoxyphenyl)ethanoic Acid; α,α-Difluoro-4-methoxyphenylacetic Acid; 2-(4-Methoxyphenyl)-2,2-difluoroacetic Acid; p-Methoxy-α,α-difluorophenylacetic Acid; DFMPA
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(4-Methoxyphenyl)Acetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.