Description

2,6-Dichloro-3-(Trifluoromethyl)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and chloro substituents contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs), liquid crystals, and polymers with specific electronic properties.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl bonds, a fundamental transformation in medicinal and process chemistry.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2,6-Dichloro-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1027059-21-7
Molecular Formula	C7H4BCl2F3O2
Molecular Weight	272.82 g/mol
Synonyms	(2,6-Dichloro-3-(trifluoromethyl)phenyl)boronic acid; 2,6-Dichloro-3-trifluoromethylbenzeneboronic acid; B-[2,6-Dichloro-3-(trifluoromethyl)phenyl]boronic acid; 2,6-Dichloro-alpha,alpha,α-trifluoro-m-tolylboronic acid; 3-Borono-2,6-dichlorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.