Description

3-Ethoxy-4-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs), especially those containing the trifluoromethyl group for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a precursor in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the creation of novel boron-containing ligands and catalysts for asymmetric synthesis.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting for new chemical entities.
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-Ethoxy-4-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1026796-35-9
Molecular Formula	C9H10BF3O3
Molecular Weight	233.98 g/mol
Synonyms	(3-Ethoxy-4-(trifluoromethyl)phenyl)boronic acid; 3-Ethoxy-4-trifluoromethylbenzeneboronic acid; B-[3-Ethoxy-4-(trifluoromethyl)phenyl]boronic acid; 4-Trifluoromethyl-3-ethoxyphenylboronic acid; 3-Ethoxy-α,α,α-trifluoro-p-tolylboronic acid; 3-Ethoxy-4-(trifluoromethyl)benzeneboronic acid; Boronic acid, B-[3-ethoxy-4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-4-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.