Description

4-(3,5-Dichlorophenyl)Benzonitrile is a high-value, halogenated aromatic nitrile building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing biaryl systems common in kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and pesticides, leveraging the dichlorophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig couplings.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the benzonitrile and dichlorophenyl groups impart specific electronic and structural properties.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or molecular probes for biological imaging and diagnostic applications.

Basic Information

Product Name	4-(3,5-Dichlorophenyl)Benzonitrile
CAS No.	1025992-48-6
Molecular Formula	C13H7Cl2N
Molecular Weight	248.11 g/mol
Synonyms	[4-(3,5-Dichlorophenyl)phenyl]acetonitrile; 4-(3,5-Dichlorophenyl)benzonitrile; 3',5'-Dichloro[1,1'-biphenyl]-4-carbonitrile; 4-(3,5-Dichlorophenyl)phenyl cyanide; p-(3,5-Dichlorophenyl)benzonitrile; Biphenyl-4-carbonitrile, 3',5'-dichloro-; (4-(3,5-Dichlorophenyl)phenyl)methanenitrile
EINECS	Contact for details

Quality Control

Our 4-(3,5-Dichlorophenyl)Benzonitrile is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.