Description

(E)-2-(tert-Butylsulfonyl)-3-[4-(Trifluoromethyl)Anilino]-2-Propenenitrile is a high-value, specialized organic intermediate featuring a unique sulfonyl and trifluoromethyl-substituted anilino propenenitrile structure. This compound is critical for advanced chemical synthesis, offering a versatile building block for constructing complex molecules with tailored electronic and steric properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the trifluoromethyl and sulfonyl groups can enhance biological activity and stability.
• Material Science: Acts as a monomer or functional additive in the creation of advanced polymers, liquid crystals, or organic semiconductors.
• Chemical Synthesis: Employed as a versatile electrophile or Michael acceptor in organic reactions to introduce complex sulfonamide and nitrile functionalities.
• Life Science Research: Utilized as a biochemical probe or tool compound for studying biological pathways and protein interactions in academic and industrial R&D.

Basic Information

Product Name	(E)-2-(tert-Butylsulfonyl)-3-[4-(Trifluoromethyl)Anilino]-2-Propenenitrile
CAS No.	1024891-50-6
Molecular Formula	C₁₅H₁₇F₃N₂O₂S
Molecular Weight	346.37 g/mol
Synonyms	(E)-2-(tert-Butylsulfonyl)-3-[(4-(trifluoromethyl)phenyl)amino]-2-propenenitrile; 2-Propenenitrile, 2-[(1,1-dimethylethyl)sulfonyl]-3-[[4-(trifluoromethyl)phenyl]amino]-, (2E)-; (E)-2-(tert-Butylsulfonyl)-3-(4-(trifluoromethyl)phenylamino)acrylonitrile; 2-(tert-Butylsulfonyl)-3-(4-trifluoromethylanilino)acrylonitrile (E-isomer); TBSPAN; tert-Butylsulfonyl Trifluoromethyl Anilino Propenenitrile
EINECS	Contact for details

Quality Control

Our production of (E)-2-(tert-Butylsulfonyl)-3-[4-(Trifluoromethyl)Anilino]-2-Propenenitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and scale-up projects with material produced under a quality management system designed to meet the exacting standards of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.