Description

5-(Dimethylamino)-2-(2,2,2-trifluoroacetyl)penta-2,4-dienenitrile is a specialized organic compound featuring a unique conjugated dienenitrile structure functionalized with dimethylamino and trifluoroacetyl groups. This molecular architecture makes it a valuable high-purity building block and key intermediate in advanced synthetic chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing fluorinated motifs and heterocyclic systems.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where its structural elements can contribute to biological activity and metabolic stability.
• Organic Synthesis Building Block: Employed in cyclization reactions, [4+2] cycloadditions, and as a substrate for creating complex, polyfunctional molecules in academic and industrial research.
• Material Science Precursor: Potential use in the synthesis of specialized organic ligands, dyes, or functional polymers that require specific electronic properties.
• Fluorine Chemistry: Acts as a source of the trifluoroacetyl group for introducing fluorine atoms into target molecules, a common strategy to modulate lipophilicity and bioavailability.

Basic Information

Product Name	5-(Dimethylamino)-2-(2,2,2-trifluoroacetyl)penta-2,4-dienenitrile
CAS No.	1022901-66-1
Molecular Formula	C10H9F3N2O
Molecular Weight	230.19 g/mol
Synonyms	2-(2,2,2-Trifluoroacetyl)-5-(dimethylamino)penta-2,4-dienenitrile; 5-(Dimethylamino)-2-(trifluoroacetyl)-2,4-pentadienenitrile; (E)-5-(Dimethylamino)-2-(2,2,2-trifluoroacetyl)penta-2,4-dienenitrile; 2,4-Pentadienenitrile, 5-(dimethylamino)-2-(trifluoroacetyl)-; TFA-DMAPDN; DMAP-TFADN; Trifluoroacetyl dimethylaminopentadienenitrile
EINECS	Contact for details

Quality Control

Our production of 5-(Dimethylamino)-2-(2,2,2-trifluoroacetyl)penta-2,4-dienenitrile adheres to a stringent quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets exacting R&D and process chemistry standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to air; it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.