Description

4-Acetyl-2-Fluorophenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling its use as a versatile coupling partner in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex fluorinated and acetylated aromatic scaffolds for active ingredient development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic rings.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a reliable boron reagent for forming carbon-carbon bonds with aryl halides, a cornerstone of medicinal chemistry and material science.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Ligand and Catalyst Development: Acts as a starting material for creating novel bidentate ligands and organoboron catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	4-Acetyl-2-Fluorophenylboronic Acid
CAS No.	1022154-78-4
Molecular Formula	C8H8BFO3
Molecular Weight	181.96 g/mol
Synonyms	(4-Acetyl-2-fluorophenyl)boronic acid; 2-Fluoro-4-acetylbenzeneboronic acid; 4-Acetyl-2-fluorobenzeneboronic acid; Boronic acid, B-(4-acetyl-2-fluorophenyl)-; 1022154-78-4; 4-Acetyl-2-fluoro phenylboronic acid; 2-Fluoro-4-acetylphenylboronic acid
EINECS	Contact for details

Quality Control

Our production of 4-Acetyl-2-Fluorophenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.