Description

2-Butenoic Acid, 4-[4-[2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]Ethyl]-1-Piperazinyl]- is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture combining a piperazine ring with a protected amino acid moiety. This compound matters for its critical role as a sophisticated building block in the synthesis of targeted active pharmaceutical ingredients (APIs), enabling precise molecular modifications. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring specific receptor targeting or pharmacokinetic optimization.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical research.
• Protease Inhibitor Research: Used in the development of novel inhibitors targeting specific enzymatic pathways.
• GPCR-Targeted Drug Discovery: Serves as a precursor for ligands targeting G-protein-coupled receptors due to its piperazine core.
• Peptidomimetic Synthesis: Integral component for creating peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized, non-commercial drug candidates.

Basic Information

Product Name	2-Butenoic Acid, 4-[4-[2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]Ethyl]-1-Piperazinyl]-
CAS No.	1022150-13-5
Molecular Formula	C15H27N3O4
Molecular Weight	313.40 g/mol
Synonyms	4-[4-[2-[(tert-Butoxycarbonyl)amino]ethyl]piperazin-1-yl]but-2-enoic acid; (E)-4-(4-(2-((tert-Butoxycarbonyl)amino)ethyl)piperazin-1-yl)but-2-enoic acid; Boc-Piperazine-Butenoic Acid derivative; tert-Butyl (2-(4-(4-carboxybut-2-en-1-yl)piperazin-1-yl)ethyl)carbamate; 1022150-13-5; Advanced Piperazine Intermediate; Protected Amino Acid-Piperazine Conjugate
EINECS	Contact for details

Quality Control

Our 2-Butenoic Acid, 4-[4-[2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]Ethyl]-1-Piperazinyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.