Description

3-(Bromomethyl)-4-Chlorobenzonitrile is a versatile halogenated benzonitrile derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its dual reactive sites, the bromomethyl and chlorophenyl groups, which enable selective functionalization to create complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), intermediates, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating libraries of bioactive molecules.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Intermediate in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(Bromomethyl)-4-Chlorobenzonitrile
CAS No.	1021871-37-3
Molecular Formula	C8H5BrClN
Molecular Weight	230.49 g/mol
Synonyms	4-Chloro-3-(bromomethyl)benzonitrile; 3-Bromomethyl-4-chlorobenzonitrile; 4-Chloro-3-bromomethylbenzonitrile; 2-Chloro-5-cyanobenzyl bromide; Benzonitrile, 4-chloro-3-(bromomethyl)-; (4-Chloro-3-cyanophenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our 3-(Bromomethyl)-4-Chlorobenzonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.