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4-Methyl-2-Trifluoromethyl-Phenylboronic Acid CAS NO 1021860-94-5
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CAS No.:1021860-94-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Methyl-2-Trifluoromethyl-Phenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in enabling the efficient construction of complex molecular architectures, particularly those containing the trifluoromethyl group, which is highly sought after for its ability to modulate the physical and biological properties of target molecules. This boronic acid is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for Suzuki-Miyaura cross-coupling reactions.
Application
- Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling.
- Building block for creating agrochemicals, such as herbicides and fungicides, with enhanced metabolic stability.
- Precursor in the development of liquid crystal materials and organic light-emitting diodes (OLEDs) for electronic displays.
- Used in medicinal chemistry research for constructing compound libraries to explore structure-activity relationships (SAR).
- Intermediate in the production of specialty polymers and advanced organic materials.
- Starting material for synthesizing ligands and catalysts used in asymmetric synthesis.
Basic Information
| Product Name | 4-Methyl-2-Trifluoromethyl-Phenylboronic Acid |
| CAS No. | 1021860-94-5 |
| Molecular Formula | C9H8BF3O2 |
| Molecular Weight | 216.97 g/mol |
| Synonyms | (4-Methyl-2-(trifluoromethyl)phenyl)boronic acid; 2-Trifluoromethyl-4-methylbenzeneboronic acid; 4-Methyl-2-trifluoromethylbenzeneboronic acid; 2-(Trifluoromethyl)-4-methylphenylboronic acid; Boronic acid, B-[4-methyl-2-(trifluoromethyl)phenyl]-; 1021860-94-5; 4-Methyl-α,α,α-trifluoro-o-tolueneboronic acid |
| EINECS | Contact for details |
Quality Control
Our 4-Methyl-2-Trifluoromethyl-Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥97.0% |
| Water Content (KF) | ≤1.0% |
| Melting Point | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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