Description

(11Br)-8,9,10,11,12,13,14,15-Octahydro-N,n-Bis[(1S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is a sophisticated chiral organophosphorus compound featuring a unique dinaphthodioxaphosphepine core structure. This compound matters as a high-value specialty ligand or catalyst precursor in advanced asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal catalysts in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Pharmaceutical Intermediate Synthesis: A key building block or chiral auxiliary in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Agrochemical Research: Used in the development of novel, stereospecific herbicides, fungicides, and insecticides.
• Material Science: Potential application in the synthesis of chiral polymers or as a dopant for advanced optical materials.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry research laboratories.
• Process Chemistry Optimization: Evaluation and scale-up of new catalytic cycles for more efficient and sustainable chemical manufacturing.

Basic Information

Product Name	(11Br)-8,9,10,11,12,13,14,15-Octahydro-N,n-Bis[(1S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine
CAS No.	1021439-60-0
Molecular Formula	C37H37BrNO2P
Molecular Weight	638.58 g/mol
Synonyms	(11-Bromo-8,9,10,11,12,13,14,15-octahydro-N,N-bis[(1S)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine); 4-Amino-11-bromo-8,9,10,11,12,13,14,15-octahydro-N,N-bis[(1S)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; Chiral Dinaphthodioxaphosphepine Amine Derivative; Brominated BINOL-Derived Phosphoramidite Ligand Analog; (S,S)-11-Br-H8-BINAPO-Type Ligand Precursor
EINECS	Contact for details

Quality Control

Every batch of this advanced chiral chemical is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral integrity, supported by analytical techniques including HPLC, NMR, and chiral chromatography. Our quality systems are designed to support cGMP and ISO 9001 standards for traceability and consistency, ensuring reliable performance in critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and oxygen; for long-term storage under inert atmosphere (argon or nitrogen), please contact us.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.