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R-n-Methyl-n-[(1R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine CAS NO 1021439-57-5
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CAS No.:1021439-57-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
R-n-Methyl-n-[(1R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is a sophisticated chiral organophosphorus compound that serves as a highly effective ligand or catalyst precursor in asymmetric synthesis. Its value lies in enabling precise stereochemical control, which is critical for producing enantiomerically pure intermediates in pharmaceutical and fine chemical manufacturing. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance, stereoselective catalysts.
Application
- Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., Rh, Pd, Ir) in enantioselective hydrogenation, C-C bond formation, and other key transformations.
- Pharmaceutical Intermediate Synthesis: For the production of single-enantiomer active pharmaceutical ingredients (APIs) where stereochemical purity is mandated.
- Agrochemical Research: Development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
- Material Science: Potential use in creating chiral polymers or frameworks with specialized optical or electronic properties.
- Academic & Industrial R&D: A valuable tool for methodology development in organic and organometallic chemistry laboratories.
Basic Information
| Product Name | R-n-Methyl-n-[(1R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine |
| CAS No. | 1021439-57-5 |
| Molecular Formula | C31H26NO2P |
| Molecular Weight | 475.51 g/mol |
| Synonyms | (R)-Methyl((R)-1-phenylethyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (R,R)-Methyl(1-phenylethyl)dinaphthodioxaphosphepin-4-amine; (R,R)-MonoPhos; (R,R)-MonoPhos ligand; (4R,11bR)-4-Methyl-4-(1-phenylethyl)-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; Chiral phosphite-amine ligand; Ligand L* |
| EINECS | Contact for details |
Quality Control
Our R-n-Methyl-n-[(1R)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for catalyst and ligand applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identity are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to ensure long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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