Description

2-[(3,5-Difluorophenyl)Amino]Acetonitrile (Wxfc0627) is a high-value, specialized organic intermediate featuring a difluorophenylamino acetonitrile core structure. This compound is critical for introducing the 3,5-difluoroaniline pharmacophore into target molecules, enabling precise modulation of biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the difluorophenyl moiety enhances bioactivity and environmental stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating chemical probes and activity-based protein profiling (ABPP) agents.
• Material Science Precursor: Potential use in the synthesis of specialized polymers, liquid crystals, or organic electronic materials requiring fluorinated aromatic components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-[(3,5-Difluorophenyl)Amino]Acetonitrile (Wxfc0627)
CAS No.	1021238-97-0
Molecular Formula	C8H6F2N2
Molecular Weight	168.14 g/mol
Synonyms	2-((3,5-Difluorophenyl)amino)acetonitrile; N-(3,5-Difluorophenyl)glycinonitrile; (3,5-Difluoroanilino)acetonitrile; 2-Amino-2-(3,5-difluorophenyl)acetonitrile; WX-FC0627; Wxfc0627; Acetonitrile, 2-[(3,5-difluorophenyl)amino]-; Glycinonitrile, N-(3,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-[(3,5-Difluorophenyl)Amino]Acetonitrile is produced and tested under a strict quality management system. We guarantee high purity and consistency to meet the exacting standards of advanced organic synthesis. A comprehensive Certificate of Analysis (COA), detailing identity, purity, and impurity profiles (typically by HPLC, GC, and NMR), is provided with each shipment to ensure full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.